Mount Sinai Health System Jobs

Job Description

The Panagiotakos Lab, in the Departments of Psychiatry and Neuroscience at the Icahn School of Medicine at Mount Sinai in New York, is seeking postdoctoral fellows with expertise in calcium imaging, electrophysiology, developmental neuroscience, stem cell biology, and/or genomics/sequencing approaches to study cellular and molecular mechanisms that underlie the acquisition of cell fate during mammalian brain development. Dr. Panagiotakos' team combines multiple complementary approaches, including genetic mouse models, calcium imaging, fluorescence microscopy, pharmacology, cortical slice cultures, and various omics and biochemical analyses, to interrogate roles for ion channels, electrical activity and calcium signaling during normal development and in the context of neuropsychiatric disorders of developmental origin. The qualified candidate will use cutting-edge cellular/molecular biology, imaging and sequencing approaches in these studies, including long-isoform sequencing and live imaging, to investigate the impact of disease-relevant ion channels and calcium signaling on cellular events during brain development, including proliferation, migration and differentiation.

https://labs.icahn.mssm.edu/panagiotakoslab

Qualifications

Basic qualifications:

• PhD or MD/PhD in Developmental and Stem Cell Biology, Neuroscience, or Cellular/Molecular Biology;

• Demonstrated expertise in cellular/molecular neuroscience, developmental neuroscience, or stem cell biology;

• Record of publications in peer-reviewed journals;

• Excellent oral and written communication skills;

• Ability to work in an international and interdisciplinary team;

Experience Required:

The postdoctoral candidate must have a Ph.D. degree in the biological sciences (or proof of completion of all Ph.D. requirements prior to starting) with training/experience in developmental neuroscience, neuroscience, and/or stem cell biology and corresponding cellular/molecular biology bench skills. Preference will be given to candidates with a strong record in techniques for studying calcium signaling, including calcium imaging and electrophysiology. Experience in sequencing approaches with relevant bioinformatics skills is a major plus.

Non-Bargaining Unit, 859 - Psychiatry - ISM, Icahn School of Medicine

Responsibilities

Web link to Department: https://icahn.mssm.edu/about/departments/psychiatry Detail of Research Project:

The goals of these studies are to interrogate mechanisms by which intracellular calcium signals link

extracellular cues with intrinsic differentiation programs and to elucidate how alternative splicing refines these signals, and to investigate roles for calcium signaling pathways on cortical development.

Technical Duties: (include any protocols)

• lead independent projects focused on defining cell type specific splice isoforms and calcium signaling mechanisms

• technical toolkit will include: long-isoform sequencing, single cell RNA sequencing, genetic mouse models, calcium imaging, bioinformatics analysis, in vivo mouse surgeries, various molecular biology approaches, immunofluorescence staining and microscope

• work collaboratively and contribute to mentoring junior lab members

• cultivate scientific communication skills by contributing to the writing of grant applications and manuscripts and participating in work in progress meetings and other seminar series"

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Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

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Compensation Statement

Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.